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Laurence Longmore
2026-07-04 20:43:18 +08:00
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Compared with mouse thymocytes, mouse ES cells comprise increased levels of complete genomic H3K4me3 and have larger H3K4me3 occupancy on the promoter of the pluripotent gene Oct4 46 In agreement with this, international decreases in H3K4me3 levels happen throughout retinoic acid (RA)-induced differentiation of mouse ES cells 47 In addition, there are dynamic adjustments in H3K4me3 profiles at particular sets of genes throughout ES cell differentiation.
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